Yellow Fever
Hell beckons again when Dean is stricken with a mysterious illness that frightens its sufferers to death. Sam and Dean scramble to find the cause of the disease in time to save Dean from sure death.
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More from this season
S4 E1
Lazarus Rising
Dean wakes up in his own coffin. How did he return from the dead? What caused the hand-shaped welt on his shoulder? And what happened in the four months he spent in Hell, time he can't remember?
S4 E2
Are You There, God? It's Me, Dean Winchester
After Dean's encounter with Castiel, Dean, Sam and Bobby brush up on their biblical lore when they're attacked by the vengeful spirits of people from the Winchesters' past. They're warned it's a sign that someone is trying to break seals which will bring on the apocalypse.
S4 E3
In the Beginning
Back to the future, Castiel sends Dean to 1973 Lawrence, Kansas, where he meets a nice young couple named John and Mary Winchester. Dean's parents. And Mary has a secret.
S4 E4
Metamorphosis
Dark powers. Dean fears Sam is using his paranormal gifts in conflict with God's plan. And an ordinary guy in an ordinary town gets a major case of the munchies. It starts with steak - and moves to human flesh.